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Despite the promise of the biologic and kinase-inhibitor approaches, which are currently represented in clinical trials, both have limitations arising from toxicity or specificity considerations and/or cost

Besides the acute phase gastrointestinal effects which may lead to up to 10% of people discontinuing the drugs, there are other potential GI side effects of obstruction, excessive loss of muscle mass, and potentially association with some eye disease adverse events

doi:10.1016/j.jenvman.2010.08.028 Albini A, Alpegiani M, Borghi D et al (1995) Solid state photoreactivity of a dioxolenonemethyl ester

But this is exactly what you need to focus on first