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The combination exists only in theoretical pharmacological analysis and, likely, in unsupervised self-experimentation that produces no publishable data

doi: 10.1016/j.canlet.2015.10.010 76 LiuSLiRQianJSunJLiGShenJet al

Nonetheless, whether the specific mechanism of this is related to the transdifferentiation of VSMCs to a bone-like phenotype, loss in SMC lineage markers, enhanced pro-calcific microRNAs, increased intracellular calcium level, apoptosis, or aberrant DNA damage response (DDR) requires further investigation

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