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- *Deuruxolitinib*: The US FDA has approved deuruxolitinib, an oral JAK inhibitor, for the treatment of severe alopecia areata in adults

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suitable In-vitro release pattern was obtained wherein even with lower doses, one can deliver sufficient GHK-Cu so that at least 100 micrograms, prefearably 200 micrograms and most preferably 300 micrograms of GHK-Cu remain at the end of 24 hrs

These actions may be associated with the suppression of the signal transducer and activator of transcription 3/Notch signaling axis, downregulation of the anti-apoptotic protein B-cell lymphoma-2 (Bcl-2), and upregulation of P53 expression