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MOTS-c is also contraindicated for people who take AMPK-activating medicines, such as metformin , thiazolidinediones , and aspirin , as well as anyone with an active cancer diagnosis and people who are pregnant or breastfeeding

But to some degree in the liver

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Here we determined the rate constants for the individual redox reactions between PfGrx, a model glutaredoxin from Plasmodium falciparum , and redox-sensitive green fluorescent protein 2 (roGFP2), a model substrate and versatile tool for intracellular redox measurements