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PlexinB1/B2 activation promotes nuclear trafficking of both AR [33] and GR [34] as well as the NF-kB subunit, p65 [35] (Supplementary Fig

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3.6 Mitochondria and secretory granules Because pancreatic injury is ultimately expressed through disturbed secretion and premature enzyme activation, the consequences of mitochondrial dysfunction must also be considered within the apical secretory domain