While both medications lead to substantial weight loss, tirzepatide appears to have the edge in terms of the amount of weight lost
First, cell-type specificity: future studies should employ single-cell omics, spatial transcriptomics, and ligand-modified nanocarriers to map and manipulate ferroptotic responses in specific vascular cell types, particularly VSMCs, endothelial cells, and macrophages, to ensure selective targeting while minimizing systemic oxidative and immune side effects
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