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The mechanism appears to involve both an anti-inflammatory effect on melanocytes and normalization of the barrier function

The 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), 6-hydroxydopamine (6-OHDA), and 5-S-cysteinyl-dopamine (CysDA) models each target dopaminergic neurons and increase oxidative damage to the brain, providing valuable insight to the efficacy of mitigating oxidative stress as a mechanism of sulforaphanes neuroprotective effects

Kwon DR, Park GY

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