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Prados MD, Schold SC Jr, Fine HA, Jaeckle K, Hochberg F, Mechtler L, Fetell MR, Phuphanich S, Feun L, Janus TJ, et al

The spermidine synthase (EC 2.5.1.16) mediated addition of aminopropyl from decarboxylated s-adenosylmethionine led to the synthesis of triamine spermidine and, finally, spermine synthase (EC 2.5.1.22) transfers an additional aminopropyl group to form the tetramine spermine [126]

doi: 10.1074/jbc.RA119.008180 21 WickerCAHuntBGKrishnanSAzizKParajuliSPalackdharrySet al

Also, vitamin C, selenium, alpha lipoic, broccolli seed extract, curcumin, resveratrol, grape seed extract, quercetin, milk thistle seed extract, cordyceps, black pepper, aloe leaf are present to complement this effort [40]