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doi: 10.1016/0165-1781(91)90116-7 37 AliciDBulbulFViritOUnalAAltindagAAlpakGet al
Problems with taurine metabolism are linked to various diseases, including metabolic syndrome, heart disease, neurodegenerative disorders, gut problems, and even cancer, suggesting it could have preventive and therapeutic benefits
Overall, redox signaling involving mtROS, the PRX3SRX axis, HIF-1, NRF2, and the NOXNADPH system constitutes a regulatory network through which mitochondrial dysfunction is communicated to the ER, nucleus, lysosomes, and peroxisomes, thereby amplifying organellar stress and shaping cell fate in AP (24, 2634)