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Additionally, certain medical interventions, particularly cancer immunotherapies using immune-checkpoint inhibitors (ICIs), have been reported to precipitate autoimmune thyroiditis by enhancing T-cellmediated immune responses and breaking self-tolerance (Barroso-Sousa et al

D.ZhouJ

Prevalence of moderate hyperhomocysteinemia in patients with early-onset venous and arterial occlusive disease

We can't extrapolate direct safety conclusions, but the absence of chronic toxicity signals in extended animal models is at least directionally reassuring