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This is particularly relevant after rotator cuff repair surgery, where the quality of tendon-bone healing directly determines whether the repair holds or retears

Standard Protocol (Weeks 5-12) Daily Dose : 400 mcg subcutaneous injection Timing : Morning, fasted state preferred Frequency : Once daily Duration : 8-12 weeks continuous use The 400 mcg dose represents the optimal balance between efficacy and tolerability for most individuals

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Additionally, confinement triggers resistance to chemotherapeutics [198] and to programmed cell death triggered by loss of adhesion (aka anoikis) [199] which in turn facilitates breast cancer metastasis [199]