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Acetaminophen-induced hepatic injury in mice: the role of lipid peroxidation and effects of pretreatment with coenzyme Q10 and alpha-tocopherol

Kincaid, S., Stickling, C

Despite this, biological effects on VEGFR2 signaling, EGR-1 transcription, and tissue repair persist for hours to days after a single dose, suggesting effects are mediated by rapid signaling cascades whose downstream consequences outlast the parent compound