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This age-related decline is one of the most frequently cited data points in copper-peptide research literature, and its a primary reason GHK-Cu is studied within the broader context of cellular aging and peptides for longevity research rather than treated purely as a wound-healing or dermatology compound

However, Gal- 3 neutralising antibody treatment has been reported to reduce trauma-induced increases in pro-inflammatory markers such as IL- 1, IL- 6 and TNF-, supporting neuroprotection in cortical and hippocampal cell populations after head injury