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During an initial consultation, a doctor will review the patients health history, goals, and reasonable expectations for treatment

- Inject in the superior external quadrant of the buttock, in a perpendicular direction to the iliac spine

The AAFPs evidence-based clinical review states directly: Oral administration of high-dose vitamin B12 (1 to 2 mg daily) is as effective as intramuscular administration for correcting anemia and neurologic symptoms in patients with B12 deficiency (Langan RC, Goodbred AJ, American Family Physician, 2017)

From injecting into fat instead of muscle to reusing needles, here is what can go wrong with poor B12 injection technique, and why it is safer in trained hands