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Stage 3: Low vitamin B-12 and neurological and psychological symptoms such as paresthesias, balance problems, confusion, and depression

In our study we only detected co-localisation and increased staining of three other proteins (GP-1, GADD45 and 8-OhDG) within bulbar melanocytes

Moreover, OPA1 forms connections and aggregates through the G domain, similar to MFN, or unique interfaces through the BSE domain, promoting the fusion and protrusion of IMM to form new mitochondrial cristae [63]

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