As for heated tobacco products, compared to 2018, smokers who say they have never tried them have decreased by 12 percentage points (from 75% to 62.7%), consequently, Italians who have only tried them are on the rise (from 19% to 22.2%) and, even more, those who have used them (more than doubled compared to 2018) and those who use them regularly (4%), which tripled compared to the previous survey, when they stopped at 1.2%
Distribution of historical and current patient share based on real-world prescription data along with reported sales of approved products in the US, EU4 (Germany, France, Italy, and Spain), the United Kingdom, and Japan
Therefore, the contribution of ammonia to the alkalinity of cigarette smoke is considered to be low