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Similarly, TB-500 has undergone extensive safety evaluation including human research trials showing safety at intravenous doses up to 1,260 mg equivalent, with no dose-limiting toxicities or serious adverse events attributable to the peptide in carefully controlled studies

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According to the Mounjaro Summary of Product Characteristics (SmPC), these two treatments do not have a known direct pharmacological interaction, as they work through entirely different mechanisms and are metabolised via separate pathways