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These studies indicate that VacA may contribute to the ferroptosis in GC progression by increasing ROS levels and disrupting the metabolism of GSH through various mechanisms, but there is no reports on the morphology and related proteins of ferroptosis cells with VacA, which is worthy of further investigation

MTHFR and Glutathione One reason that MTHFR variants are linked to a variety of illnesses is their common pathway and connection to glutathione production