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This blunting of the microglial response attenuated reactivity to LPS and, furthermore, altered behavior in mice, where exposed mice showed an inability to react appropriately to psychosocial stress (Lee et al., 2022)

In brief, cell or tissue protein lysates were assayed in transparent 96-well plates (Greiner, 655101) in the presence of 1 mM of the GGT substrate l-glutamic acid -p-nitroanilide (GpNA

Researchers investigating steroid-related endocrine conditions have measured alterations in the steroid metabolome for several decades

The modulation of iron and lipid metabolic pathways to induce ferroptosis may provide a synergistic effect when combined with immunotherapeutic approaches [86]