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Regulation of cell surface transferrin receptor-2 by iron-dependent cleavage and release of a soluble form

Among these factors, the dynamic balance of iron and the abnormality of lipid peroxidation are the most important to induce ferroptosis, while the functional state of System X c and the activity level of GPX4 are the key pathways to regulate ferroptosis

The considerable effects of non-selective TKIs, especially crizotinib, led to the US Food and Drug Administration (FDA) approval of crizotinib in ALK+ cancers [166]

A recent detailed procedure described the use of equal volumes (20 ml) of 8.2% and 17.6% (w/v) iodixanol [5]