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Retina blood flow was evaluated using fluorescein angiography and was significantly lower compared to that of non-diabetic subjects
It is likely that the most well-known function of NADPH oxidase-derived superoxide is the inactivation of NO in the reaction that forms peroxynitrite, which leads to impaired endothelium dependent vasodilation and the uncoupling of endothelial NO synthase (eNOS) to produce additional superoxide
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The results showed that TGF1 stimulation increased the level of oxidized lipids, as indicated by intensified green fluorescence (Fig
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