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It is proposed that GSPs inhibit NF-B activation by inhibiting the activation of IK (inhibitor of B kinase) to prevent phosphorylation-induced degradation of IB (196)

Studies comparing PRP to corticosteroids found: A randomized trial of 192 patients with knee OA found that PRP provided superior long-term pain relief compared to corticosteroids , with no evidence of cartilage degradation (PMID: 33239706)