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CYP1A2, 2A6, 2C9, 2D6, 2E1, and 3A4 isoforms also play a role in the metabolism of bupropion, but to a lesser extent ( Oxidation of bupropion side chain results in the formation of a glycine conjugate of metachlorobenzoic acid, which is then excreted as the major urinary metabolite

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With its strong tobacco heritage and brand recognition, Lambert & Butler is well placed to respond to this trend with its new RYO variant, Street added