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A diferencia de las protenas estructurales o funcionales, la L-Carnitina no se incorpora a tejidos de forma permanente, sino que acta como una molcula transportadora

Desmoulire, A., Redard, M., Darby, I., & Gabbiani, G

In addition, senescent cells gain an irreversible senescence-associated secretory phenotype (SASP), secreting soluble factors (such as chemokines and interleukins) and matrix-degrading enzymes, altering the microenvironment and affecting the behavior of the surrounding cells (120, 121)

The hurdle of expanding their clinical indications by targeting PGC-1 involves toxicology analyses, dosing, and formulation optimization