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Funding This work was supported by the National Natural Science Foundation of China (81970026, 82000029), China Postdoctoral Science Foundation (2023M730799), Chengdu High-level Key Clinical Specialty Construction Project (ZX20201202020), Chengdu Science and Technology Bureau (2021-YF09-00102-SN), Sichuan provincial administration of traditional Chinese medicine (2020JC0118, 2020LC0212)