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Regarding corticosterone levels, which directly indicate stress in murine models, a decrease was noted shortly after DSIP exposure

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Coronary atherosclerosis initiates with endothelial damage to the vascular intima, followed by a sequence of events including lipid deposition, vascular smooth muscle cell proliferation, and extracellular matrix synthesis, collectively resulting in arterial wall thickening and progressive luminal narrowing ( Thrombosis represents another critical aspect in acute CHD manifestations