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12.3 , bottom) is a freely reversible equilibrium reaction, yielding two triose phosphates, dihydroxyacetone phosphate and glyceraldehyde-3-phosphate, from the top and bottom halves of the Fru-1,6-BP molecule, respectively
N Engl J Med 374(3):233241 Garcia-Pavia P, Kim Y, Restrepo-Cordoba MA, Lunde IG, Wakimoto H, Smith AM, Toepfer CN, Getz K, Gorham J, Patel P, Ito K, Willcox JA, Arany Z, Li J, Owens AT, Govind R, Nuez B, Mazaika E, Bayes-Genis A, Walsh R, Finkelman B, Lupon J, Whiffin N, Serrano I, Midwinter W, Wilk A, Bardaji A, Ingold N, Buchan R, Tayal U, Pascual-Figal DA, de Marvao A, Ahmad M, Garcia-Pinilla JM, Pantazis A, Dominguez F, John BA, ORegan DP, Rosen SD, Prasad SK, Lara-Pezzi E, Provencio M, Lyon AR, Alonso-Pulpon L, Cook SA, DePalma SR, Barton PJR, Aplenc R, Seidman JG, Ky B, Ware JS, Seidman CE (2019) Genetic variants associated with cancer therapy-induced cardiomyopathy
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As a result, it breaks down on the way, and you do not get the full benefit
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