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Nicotine also changes the way synapses are formed, which can harm the parts of the brain that control attention and learning

We also estimate that a small percentage of Michigan's total cigarette market involved smuggling of Michigan cigarettes into Canada (a figure not included in the percentages above), meaning that on balance, casual and commercial smuggling into the state represented 16.0 percent of Michigan's estimated total cigarette consumption from 1990 through 2006 a little less than one in six cigarettes

doi:10.1002/14651858.CD000165.pub4 Toll BA, Rojewski AM, Duncan LR, et al