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The most common side effects that were seen in people with pancreatic cancer treated with ONIVYDE include: diarrhea, feeling tired (fatigue), nausea, vomiting, decreased appetite, pain around the stomach, the mucous membranes that line your mouth and gastrointestinal tract becoming inflamed (mucosal inflammation), constipation, and weight loss

The thermal energy from the vapour causes targeted cell death, and the body gradually resorbs the treated tissue, reducing obstruction

One mechanism involves reducing transforming growth factor beta-1 secretion in fibroblasts

Evidence also suggests improved function of mitochondrial enzymes such as cytochrome c oxidase, which play roles in energy metabolism and redox balance